SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2kw7 CONSERVED DOMAIN
PROTEIN
(Porphyromonas
gingivalis) 		3 / 3 PHE A 126
LEU A  90
LEU A  27
 None
 0.59A 1mx1E-2kw7A:
2.3		 1mx1E-2kw7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2kw7 CONSERVED DOMAIN
PROTEIN
(Porphyromonas
gingivalis) 		3 / 3 SER A  45
SER A  46
HIS A 155
 None
 0.66A 3mzeA-2kw7A:
undetectable		 3mzeA-2kw7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 2kw7 CONSERVED DOMAIN
PROTEIN
(Porphyromonas
gingivalis) 		5 / 12 ARG A  19
ASP A  23
GLY A  26
ALA A  25
PRO A  10
 None
 1.03A 3nu5B-2kw7A:
undetectable		 3nu5B-2kw7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 2kw7 CONSERVED DOMAIN
PROTEIN
(Porphyromonas
gingivalis) 		5 / 12 LEU A  88
ALA A  42
ILE A 117
LEU A 105
GLY A 112
 None
 1.06A 4l9qA-2kw7A:
undetectable		 4l9qA-2kw7A:
11.79