SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kxv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 2kxv TELLURITE RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		4 / 6 LEU A   9
GLU A  71
ASN A  61
TRP A  11
 None
CA  A 201 (-3.5A)
None
None
 1.46A 3i9jB-2kxvA:
undetectable		 3i9jB-2kxvA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 2kxv TELLURITE RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		4 / 8 ARG A 100
ARG A  99
GLY A 161
THR A 135
 None
 0.98A 4k87A-2kxvA:
undetectable		 4k87A-2kxvA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 2kxv TELLURITE RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		4 / 7 TYR A 125
ALA A 136
LEU A 127
PHE A 103
 None
 1.01A 4uymA-2kxvA:
undetectable		 4uymA-2kxvA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 2kxv TELLURITE RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 PHE A 139
VAL A  91
ILE A  75
VAL A   5
PHE A 151
 None
 1.29A 6ap6A-2kxvA:
undetectable		 6ap6A-2kxvA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 2kxv TELLURITE RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 PHE A 139
VAL A  91
ILE A  75
VAL A   5
PHE A 151
 None
 1.28A 6ap6B-2kxvA:
undetectable		 6ap6B-2kxvA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 2kxv TELLURITE RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		4 / 4 HIS A  57
VAL A   7
LEU A  73
ALA A  25
 None
 1.33A 6d8pB-2kxvA:
undetectable		 6d8pB-2kxvA:
14.16