SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kxw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2kxw CALMODULIN
(Paramecium
tetraurelia) 		4 / 8 PHE A  89
MET A 109
THR A 110
LEU A 116
 None
 0.90A 3abmN-2kxwA:
undetectable
3abmW-2kxwA:
undetectable		 3abmN-2kxwA:
8.77
3abmW-2kxwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2kxw CALMODULIN
(Paramecium
tetraurelia) 		4 / 7 PHE A  89
MET A 109
THR A 110
LEU A 116
 None
 0.91A 5iy5N-2kxwA:
undetectable
5iy5W-2kxwA:
undetectable		 5iy5N-2kxwA:
8.77
5iy5W-2kxwA:
20.55