SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ky4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2ky4 PHYCOBILISOME LINKER
POLYPEPTIDE
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE A 106
PHE A 115
GLY A 111
LEU A  69
TYR A  68
 None
 1.41A 1fm6X-2ky4A:
undetectable		 1fm6X-2ky4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2ky4 PHYCOBILISOME LINKER
POLYPEPTIDE
(Nostoc
sp.
PCC
7120) 		3 / 3 VAL A 134
VAL A   3
ASP A  12
 None
 0.76A 2fumD-2ky4A:
undetectable		 2fumD-2ky4A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2ky4 PHYCOBILISOME LINKER
POLYPEPTIDE
(Nostoc
sp.
PCC
7120) 		3 / 3 LEU A  48
TRP A  44
GLY A  61
 None
 0.65A 3l35A-2ky4A:
undetectable
3l35H-2ky4A:
undetectable		 3l35A-2ky4A:
16.44
3l35H-2ky4A:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2ky4 PHYCOBILISOME LINKER
POLYPEPTIDE
(Nostoc
sp.
PCC
7120) 		3 / 3 LEU A  48
TRP A  44
GLY A  61
 None
 0.58A 3l35B-2ky4A:
undetectable
3l35K-2ky4A:
undetectable		 3l35B-2ky4A:
16.44
3l35K-2ky4A:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 2ky4 PHYCOBILISOME LINKER
POLYPEPTIDE
(Nostoc
sp.
PCC
7120) 		3 / 3 ARG A  30
LEU A  67
THR A  74
 None
 0.71A 3oxcA-2ky4A:
undetectable		 3oxcA-2ky4A:
20.92