SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kyf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OLT_A_SAMA501_0 (OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE)	2kyf	PARVALBUMIN, THYMIC CPV3 (Gallus gallus)	5 / 12	GLY A 93 ASP A 94 ILE A 97 ALA A 99 GLN A 103	None CA A 110 (-3.4A) None None None	1.19A	1oltA-2kyfA: undetectable	1oltA-2kyfA: 14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_A_SAMA500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2kyf	PARVALBUMIN, THYMIC CPV3 (Gallus gallus)	5 / 11	GLU A 100 ALA A 99 ILE A 58 ALA A 89 ASP A 51	None None None None CA A 109 (-3.1A)	1.33A	2admA-2kyfA: undetectable	2admA-2kyfA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_B_SAMB500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2kyf	PARVALBUMIN, THYMIC CPV3 (Gallus gallus)	5 / 11	GLU A 100 ALA A 99 ILE A 58 ALA A 89 ASP A 51	None None None None CA A 109 (-3.1A)	1.32A	2admB-2kyfA: undetectable	2admB-2kyfA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP9_C_1WEC706_1 (TRANSPORTER)	2kyf	PARVALBUMIN, THYMIC CPV3 (Gallus gallus)	4 / 4	PHE A 57 ASP A 51 GLY A 98 SER A 55	None CA A 109 (-3.1A) None CA A 109 (-2.7A)	1.49A	4xp9C-2kyfA: undetectable	4xp9C-2kyfA: 9.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OLT_A_SAMA501_0","OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE","2kyf","PARVALBUMIN, THYMIC CPV3","Gallus gallus",5,"GLY A  93;ASP A  94;ILE A  97;ALA A  99;GLN A 103","None; CA A 110 (-3.4A);None;None;None","1.19A","1oltA-2kyfA:undetectable","1oltA-2kyfA:14.00"],["2ADM_A_SAMA500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2kyf","PARVALBUMIN, THYMIC CPV3","Gallus gallus",5,"GLU A 100;ALA A  99;ILE A  58;ALA A  89;ASP A  51","None;None;None;None; CA A 109 (-3.1A)","1.33A","2admA-2kyfA:undetectable","2admA-2kyfA:14.85"],["2ADM_B_SAMB500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2kyf","PARVALBUMIN, THYMIC CPV3","Gallus gallus",5,"GLU A 100;ALA A  99;ILE A  58;ALA A  89;ASP A  51","None;None;None;None; CA A 109 (-3.1A)","1.32A","2admB-2kyfA:undetectable","2admB-2kyfA:14.85"],["4XP9_C_1WEC706_1","TRANSPORTER","2kyf","PARVALBUMIN, THYMIC CPV3","Gallus gallus",4,"PHE A  57;ASP A  51;GLY A  98;SER A  55","None; CA A 109 (-3.1A);None; CA A 109 (-2.7A)","1.49A","4xp9C-2kyfA:undetectable","4xp9C-2kyfA:9.53"]]