SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kyh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 2kyh VOLTAGE-GATED
POTASSIUM CHANNEL
(Aeropyrum
pernix) 		4 / 4 ASP A  62
LEU A  69
LEU A  97
LEU A  65
 None
 1.27A 1u18A-2kyhA:
undetectable		 1u18A-2kyhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2kyh VOLTAGE-GATED
POTASSIUM CHANNEL
(Aeropyrum
pernix) 		4 / 6 LEU A  29
SER A  32
TYR A  33
LEU A  36
 None
 0.57A 3f33A-2kyhA:
3.6		 3f33A-2kyhA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 2kyh VOLTAGE-GATED
POTASSIUM CHANNEL
(Aeropyrum
pernix) 		4 / 6 SER A 135
ALA A 140
SER A 139
ALA A  35
 None
 0.86A 6bocA-2kyhA:
undetectable
6bocB-2kyhA:
undetectable
6bocC-2kyhA:
undetectable
6bocD-2kyhA:
undetectable		 6bocA-2kyhA:
13.79
6bocB-2kyhA:
13.79
6bocC-2kyhA:
13.79
6bocD-2kyhA:
13.79