SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1LIN_A_TFPA154_1 (CALMODULIN)	2kz2	CALMODULIN (Gallus gallus)	4 / 7	MET A 109 GLU A 114 LEU A 116 MET A 124	None	1.01A	1linA-2kz2A: 9.3	1linA-2kz2A: 59.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1LXF_C_BEPC92_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2kz2	CALMODULIN (Gallus gallus)	6 / 12	ILE A 100 LEU A 105 MET A 109 VAL A 136 MET A 144 MET A 145	None None None CA A 150 (-4.1A) None None	1.14A	1lxfC-2kz2A: 7.2	1lxfC-2kz2A: 35.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYZ_A_CCSA109_0 (CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES)	2kz2	CALMODULIN (Gallus gallus)	4 / 8	TYR A 99 ASN A 137 PHE A 141 VAL A 142	None CA A 150 ( 4.6A) None None	0.94A	4eyzA-2kz2A: undetectable	4eyzA-2kz2A: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYZ_B_CCSB109_0 (CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES)	2kz2	CALMODULIN (Gallus gallus)	4 / 8	TYR A 99 ASN A 137 PHE A 141 VAL A 142	None CA A 150 ( 4.6A) None None	0.95A	4eyzB-2kz2A: undetectable	4eyzB-2kz2A: 17.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LIN_A_TFPA154_1","CALMODULIN","2kz2","CALMODULIN","Gallus gallus",4,"MET A 109;GLU A 114;LEU A 116;MET A 124","None","1.01A","1linA-2kz2A:9.3","1linA-2kz2A:59.85"],["1LXF_C_BEPC92_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2kz2","CALMODULIN","Gallus gallus",6,"ILE A 100;LEU A 105;MET A 109;VAL A 136;MET A 144;MET A 145","None;None;None; CA A 150 (-4.1A);None;None","1.14A","1lxfC-2kz2A:7.2","1lxfC-2kz2A:35.58"],["4EYZ_A_CCSA109_0","CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES","2kz2","CALMODULIN","Gallus gallus",4,"TYR A  99;ASN A 137;PHE A 141;VAL A 142","None; CA A 150 ( 4.6A);None;None","0.94A","4eyzA-2kz2A:undetectable","4eyzA-2kz2A:17.21"],["4EYZ_B_CCSB109_0","CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES","2kz2","CALMODULIN","Gallus gallus",4,"TYR A  99;ASN A 137;PHE A 141;VAL A 142","None; CA A 150 ( 4.6A);None;None","0.95A","4eyzB-2kz2A:undetectable","4eyzB-2kz2A:17.21"]]