SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2l01 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 PHE A  43
THR A  57
VAL A  66
LEU A  19
ILE A  15
 None
 1.23A 2xrlA-2l01A:
undetectable		 2xrlA-2l01A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 2l01 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 LEU A  68
LEU A  19
THR A  57
LEU A  50
LEU A  46
 None
 1.32A 3q1eB-2l01A:
undetectable
3q1eD-2l01A:
undetectable		 3q1eB-2l01A:
18.03
3q1eD-2l01A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 2l01 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 PHE A  42
LEU A  36
THR A  57
VAL A  55
LEU A  50
 None
 1.43A 4wnvA-2l01A:
undetectable		 4wnvA-2l01A:
10.65