SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP2_B_PNNB5002_0 (TRANSCRIPTIONAL REGULATOR TCAR)	2l02	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	4 / 5	ASN A 9 ALA A 42 ALA A 10 LYS A 51	None	1.31A	3kp2B-2l02A: 5.4	3kp2B-2l02A: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HAJ_A_DXCA75_0 (PPCA)	2l02	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	4 / 7	ILE A 25 LEU A 28 LYS A 51 GLY A 11	None	0.98A	4hajA-2l02A: undetectable	4hajA-2l02A: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R20_B_AERB602_1 (CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2)	2l02	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	5 / 9	ALA A 16 ILE A 54 VAL A 53 GLY A 22 SER A 72	None	1.12A	4r20B-2l02A: undetectable	4r20B-2l02A: 11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_D_P06D801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2l02	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	4 / 8	ILE A 63 GLY A 22 PHE A 73 PHE A 71	None	0.94A	5hieD-2l02A: undetectable	5hieD-2l02A: 15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA412_0 (UNCHARACTERIZED PROTEIN KDOO)	2l02	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	3 / 3	LYS A 12 ASN A 9 SER A 38	None	0.72A	5yw0A-2l02A: undetectable	5yw0A-2l02A: 15.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KP2_B_PNNB5002_0","TRANSCRIPTIONAL REGULATOR TCAR","2l02","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",4,"ASN A   9;ALA A  42;ALA A  10;LYS A  51","None","1.31A","3kp2B-2l02A:5.4","3kp2B-2l02A:20.26"],["4HAJ_A_DXCA75_0","PPCA","2l02","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",4,"ILE A  25;LEU A  28;LYS A  51;GLY A  11","None","0.98A","4hajA-2l02A:undetectable","4hajA-2l02A:18.29"],["4R20_B_AERB602_1","CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2","2l02","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",5,"ALA A  16;ILE A  54;VAL A  53;GLY A  22;SER A  72","None","1.12A","4r20B-2l02A:undetectable","4r20B-2l02A:11.32"],["5HIE_D_P06D801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2l02","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",4,"ILE A  63;GLY A  22;PHE A  73;PHE A  71","None","0.94A","5hieD-2l02A:undetectable","5hieD-2l02A:15.41"],["5YW0_A_ACTA412_0","UNCHARACTERIZED PROTEIN KDOO","2l02","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",3,"LYS A  12;ASN A   9;SER A  38","None","0.72A","5yw0A-2l02A:undetectable","5yw0A-2l02A:15.72"]]