SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	2l11	CHROMOBOX PROTEIN HOMOLOG 3 (Homo sapiens)	4 / 8	GLU A 38 GLU A 19 TYR A 20 ARG A 11	None	1.05A	4fgzA-2l11A: undetectable 4fgzB-2l11A: undetectable	4fgzA-2l11A: 15.02 4fgzB-2l11A: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_A_ACTA803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	2l11	CHROMOBOX PROTEIN HOMOLOG 3 (Homo sapiens)	4 / 4	GLU A 44 PRO A 43 ILE A 46 LEU A 45	None	1.11A	5m45A-2l11A: undetectable	5m45A-2l11A: 6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_D_ACTD803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	2l11	CHROMOBOX PROTEIN HOMOLOG 3 (Homo sapiens)	4 / 4	GLU A 44 PRO A 43 ILE A 46 LEU A 45	None	1.17A	5m45D-2l11A: undetectable	5m45D-2l11A: 6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_G_ACTG803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	2l11	CHROMOBOX PROTEIN HOMOLOG 3 (Homo sapiens)	4 / 4	GLU A 44 PRO A 43 ILE A 46 LEU A 45	None	1.09A	5m45G-2l11A: undetectable	5m45G-2l11A: 6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_J_ACTJ803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	2l11	CHROMOBOX PROTEIN HOMOLOG 3 (Homo sapiens)	4 / 4	GLU A 44 PRO A 43 ILE A 46 LEU A 45	None	1.19A	5m45J-2l11A: undetectable	5m45J-2l11A: 6.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FGZ_B_CQAB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","2l11","CHROMOBOX PROTEIN HOMOLOG 3","Homo sapiens",4,"GLU A  38;GLU A  19;TYR A  20;ARG A  11","None","1.05A","4fgzA-2l11A:undetectable;4fgzB-2l11A:undetectable","4fgzA-2l11A:15.02;4fgzB-2l11A:15.02"],["5M45_A_ACTA803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","2l11","CHROMOBOX PROTEIN HOMOLOG 3","Homo sapiens",4,"GLU A  44;PRO A  43;ILE A  46;LEU A  45","None","1.11A","5m45A-2l11A:undetectable","5m45A-2l11A:6.12"],["5M45_D_ACTD803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","2l11","CHROMOBOX PROTEIN HOMOLOG 3","Homo sapiens",4,"GLU A  44;PRO A  43;ILE A  46;LEU A  45","None","1.17A","5m45D-2l11A:undetectable","5m45D-2l11A:6.12"],["5M45_G_ACTG803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","2l11","CHROMOBOX PROTEIN HOMOLOG 3","Homo sapiens",4,"GLU A  44;PRO A  43;ILE A  46;LEU A  45","None","1.09A","5m45G-2l11A:undetectable","5m45G-2l11A:6.12"],["5M45_J_ACTJ803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","2l11","CHROMOBOX PROTEIN HOMOLOG 3","Homo sapiens",4,"GLU A  44;PRO A  43;ILE A  46;LEU A  45","None","1.19A","5m45J-2l11A:undetectable","5m45J-2l11A:6.12"]]