SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA206_1 (CARDIAC TROPONIN C)	2l1n	UNCHARACTERIZED PROTEIN (Synechococcus elongatus)	4 / 8	PRO A 59 GLU A 22 ASP A 20 ARG A 100	None	1.18A	1dtlA-2l1nA: undetectable	1dtlA-2l1nA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_C_VIAC903_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	2l1n	UNCHARACTERIZED PROTEIN (Synechococcus elongatus)	5 / 12	LEU A 26 ALA A 30 ALA A 113 LEU A 83 ILE A 75	None	1.11A	2h42C-2l1nA: 0.0	2h42C-2l1nA: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H79_A_T3A1_1 (THRA PROTEIN)	2l1n	UNCHARACTERIZED PROTEIN (Synechococcus elongatus)	5 / 12	ILE A 5 ILE A 3 ALA A 30 ALA A 25 LEU A 26	None	1.09A	2h79A-2l1nA: undetectable	2h79A-2l1nA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWS_X_T3X500_1 (THYROID HORMONE RECEPTOR BETA)	2l1n	UNCHARACTERIZED PROTEIN (Synechococcus elongatus)	5 / 12	ILE A 5 ILE A 3 ALA A 30 ALA A 25 LEU A 26	None	1.06A	3gwsX-2l1nA: undetectable	3gwsX-2l1nA: 18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	2l1n	UNCHARACTERIZED PROTEIN (Synechococcus elongatus)	4 / 8	LEU A 111 PRO A 59 VAL A 34 GLY A 32	None	0.98A	4klrB-2l1nA: undetectable	4klrB-2l1nA: 17.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA206_1","CARDIAC TROPONIN C","2l1n","UNCHARACTERIZED PROTEIN","Synechococcus elongatus",4,"PRO A  59;GLU A  22;ASP A  20;ARG A 100","None","1.18A","1dtlA-2l1nA:undetectable","1dtlA-2l1nA:23.38"],["2H42_C_VIAC903_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","2l1n","UNCHARACTERIZED PROTEIN","Synechococcus elongatus",5,"LEU A  26;ALA A  30;ALA A 113;LEU A  83;ILE A  75","None","1.11A","2h42C-2l1nA:0.0","2h42C-2l1nA:15.64"],["2H79_A_T3A1_1","THRA PROTEIN","2l1n","UNCHARACTERIZED PROTEIN","Synechococcus elongatus",5,"ILE A   5;ILE A   3;ALA A  30;ALA A  25;LEU A  26","None","1.09A","2h79A-2l1nA:undetectable","2h79A-2l1nA:16.67"],["3GWS_X_T3X500_1","THYROID HORMONE RECEPTOR BETA","2l1n","UNCHARACTERIZED PROTEIN","Synechococcus elongatus",5,"ILE A   5;ILE A   3;ALA A  30;ALA A  25;LEU A  26","None","1.06A","3gwsX-2l1nA:undetectable","3gwsX-2l1nA:18.87"],["4KLR_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","2l1n","UNCHARACTERIZED PROTEIN","Synechococcus elongatus",4,"LEU A 111;PRO A  59;VAL A  34;GLY A  32","None","0.98A","4klrB-2l1nA:undetectable","4klrB-2l1nA:17.57"]]