SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l1w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
GLU A 127
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 1.16A 1a29A-2l1wA:
11.5		 1a29A-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
LEU A 105
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.67A 1a29A-2l1wA:
11.5		 1a29A-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 9 ILE A 100
GLU A 127
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 1.27A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 9 ILE A 100
LEU A 105
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.84A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 9 ILE A 100
LEU A 105
MET A 124
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.89A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 9 ILE A 100
MET A 124
GLU A 127
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 1.30A 1ctrA-2l1wA:
11.2		 1ctrA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2l1w CALMODULIN
(Glycine
max) 		6 / 11 PHE A  92
ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.88A 1dtlA-2l1wA:
10.5		 1dtlA-2l1wA:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2l1w CALMODULIN
(Glycine
max) 		5 / 11 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 144
 None
 0.77A 1dtlA-2l1wA:
10.5		 1dtlA-2l1wA:
43.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA156_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 ILE A  27
LEU A  32
ILE A  52
ILE A  63
MET A  72
 None
 0.81A 1linA-2l1wA:
11.5		 1linA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA156_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
LEU A 105
MET A 124
ILE A 125
MET A 144
 None
 1.00A 1linA-2l1wA:
11.5		 1linA-2l1wA:
77.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2l1w CALMODULIN
(Glycine
max) 		6 / 12 PHE A  92
ILE A 100
LEU A 105
GLU A 127
VAL A 136
MET A 145
 None
None
None
None
CA  A 234 ( 4.6A)
None
 1.00A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2l1w CALMODULIN
(Glycine
max) 		6 / 12 PHE A  92
ILE A 100
LEU A 105
MET A 109
GLU A 127
VAL A 136
 None
None
None
None
None
CA  A 234 ( 4.6A)
 0.88A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2l1w CALMODULIN
(Glycine
max) 		6 / 12 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
VAL A 136
 None
None
None
None
None
CA  A 234 ( 4.6A)
 0.94A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2l1w CALMODULIN
(Glycine
max) 		6 / 12 PHE A  92
ILE A 100
LEU A 105
MET A 109
VAL A 136
MET A 144
 None
None
None
None
CA  A 234 ( 4.6A)
None
 0.83A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2l1w CALMODULIN
(Glycine
max) 		6 / 12 PHE A  92
ILE A 100
LEU A 105
VAL A 136
MET A 144
MET A 145
 None
None
None
CA  A 234 ( 4.6A)
None
None
 0.84A 1lxfC-2l1wA:
8.3		 1lxfC-2l1wA:
42.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2l1w CALMODULIN
(Glycine
max) 		4 / 6 PHE A  92
VAL A 108
LEU A 112
MET A 124
 None
 1.01A 1wrlB-2l1wA:
9.8		 1wrlB-2l1wA:
50.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 2l1w CALMODULIN
(Glycine
max) 		3 / 3 ASP A  95
ASP A  93
ASN A 137
 CA  A 221 (-2.3A)
CA  A 221 (-3.5A)
CA  A 234 (-3.6A)
 0.83A 4q5mA-2l1wA:
undetectable		 4q5mA-2l1wA:
21.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
LEU A 105
ALA A 128
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.72A 4rjdA-2l1wA:
10.5		 4rjdA-2l1wA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
LEU A 105
MET A 109
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.71A 4rjdA-2l1wA:
10.5		 4rjdA-2l1wA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 PHE A  92
ILE A 100
LEU A 105
MET A 124
VAL A 136
 None
None
None
None
CA  A 234 ( 4.6A)
 0.66A 4rjdA-2l1wA:
10.5		 4rjdA-2l1wA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 8 PHE A  92
ILE A 100
LEU A 105
VAL A 136
MET A 144
 None
None
None
CA  A 234 ( 4.6A)
None
 0.44A 4rjdA-2l1wA:
10.5		 4rjdA-2l1wA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 7 PHE A  92
LEU A 105
ALA A 128
MET A 144
MET A 145
 None
 0.80A 4rjdB-2l1wA:
10.3		 4rjdB-2l1wA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 7 PHE A  92
LEU A 105
MET A 109
MET A 144
MET A 145
 None
 0.81A 4rjdB-2l1wA:
10.3		 4rjdB-2l1wA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2l1w CALMODULIN
(Glycine
max) 		5 / 7 PHE A  92
LEU A 105
MET A 124
ALA A 128
MET A 145
 None
 0.89A 4rjdB-2l1wA:
10.3		 4rjdB-2l1wA:
80.60