SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 2l3j DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1
(Rattus
norvegicus) 		4 / 8 GLU A  48
GLY A  49
SER A  26
THR A  28
 None
 0.84A 1m4iA-2l3jA:
undetectable		 1m4iA-2l3jA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 2l3j DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1
(Rattus
norvegicus) 		5 / 12 PRO A 152
PHE A 155
GLY A 203
SER A 204
ALA A 219
 None
 1.19A 1nw5A-2l3jA:
undetectable		 1nw5A-2l3jA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 2l3j DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1
(Rattus
norvegicus) 		5 / 12 GLN A  12
LEU A  10
LEU A  13
GLU A  63
LEU A  59
 None
G  B 277 ( 3.5A)
None
None
None
 1.25A 5nwwA-2l3jA:
undetectable		 5nwwA-2l3jA:
14.29