SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		4 / 7 ASP A 117
ARG A  52
VAL A  55
TYR A 121
 None
 0.89A 2yfbA-2l3wA:
undetectable		 2yfbA-2l3wA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		5 / 12 LEU A  85
VAL A  21
TYR A  22
PHE A  54
TYR A 121
 None
 1.49A 4idkA-2l3wA:
undetectable		 4idkA-2l3wA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		5 / 12 LEU A  85
VAL A  21
TYR A  22
PHE A  54
TYR A 121
 None
 1.50A 4ifyA-2l3wA:
undetectable		 4ifyA-2l3wA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		5 / 12 LEU A  85
VAL A  21
TYR A  22
PHE A  54
TYR A 121
 None
 1.49A 4kfbA-2l3wA:
undetectable		 4kfbA-2l3wA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		4 / 4 ALA A  94
ALA A  97
ALA A  98
ALA A 101
 None
 0.13A 4oadA-2l3wA:
undetectable		 4oadA-2l3wA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		4 / 4 ALA A  94
ALA A  97
ALA A  98
ALA A 101
 None
 0.12A 4oaeA-2l3wA:
undetectable		 4oaeA-2l3wA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		5 / 12 LEU A  85
VAL A  21
TYR A  22
PHE A  54
TYR A 121
 None
 1.49A 5cymA-2l3wA:
undetectable		 5cymA-2l3wA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		4 / 7 PRO A 131
TYR A 121
PHE A  54
SER A  61
 None
 1.25A 5l1fC-2l3wA:
undetectable		 5l1fC-2l3wA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		3 / 3 HIS A 138
HIS A 139
ARG A  23
 None
 1.08A 6b58A-2l3wA:
undetectable		 6b58A-2l3wA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2l3w PHYCOBILISOME ROD
LINKER POLYPEPTIDE
(Synechococcus
elongatus) 		5 / 12 LEU A  85
VAL A  21
TYR A  22
PHE A  54
TYR A 121
 None
 1.49A 6eliA-2l3wA:
undetectable		 6eliA-2l3wA:
17.91