SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 2l48 N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Bacillus
phage
Gamma) 		4 / 7 VAL A 232
TYR A 230
LYS A 217
GLU A 221
 None
 1.01A 3hs4A-2l48A:
undetectable		 3hs4A-2l48A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 2l48 N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Bacillus
phage
Gamma) 		4 / 5 SER A 172
MET A 192
LEU A 187
PHE A 196
 None
 1.40A 5evyX-2l48A:
undetectable		 5evyX-2l48A:
12.01