SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 2l4v CYSTATIN
(Ananas
comosus) 		4 / 7 VAL A  90
VAL A  91
GLY A  93
LYS A 114
 None
 0.98A 3bjwC-2l4vA:
undetectable		 3bjwC-2l4vA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 2l4v CYSTATIN
(Ananas
comosus) 		4 / 8 VAL A  90
VAL A  91
GLY A  93
LYS A 114
 None
 0.90A 3bjwA-2l4vA:
undetectable		 3bjwA-2l4vA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2l4v CYSTATIN
(Ananas
comosus) 		5 / 12 ALA A 113
PHE A 129
LEU A  78
ALA A  63
VAL A 102
 None
 0.95A 3rukA-2l4vA:
undetectable		 3rukA-2l4vA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 2l4v CYSTATIN
(Ananas
comosus) 		5 / 12 LEU A  62
GLY A  56
ASN A  53
LEU A  51
ALA A  86
 None
 1.34A 5kc4E-2l4vA:
undetectable		 5kc4E-2l4vA:
19.13