SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		4 / 8 LEU A  90
THR A 107
VAL A  47
GLY A  84
 None
 0.86A 3dcjB-2l5eA:
undetectable		 3dcjB-2l5eA:
19.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		7 / 7 TRP A  57
PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 1.01A 3u5jA-2l5eA:
17.4		 3u5jA-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 0.87A 3u5kA-2l5eA:
17.3		 3u5kA-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 TRP A  57
PRO A  58
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 0.87A 3u5kA-2l5eA:
17.3		 3u5kA-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 7 TRP A  57
PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
 None
 0.85A 3u5kB-2l5eA:
17.0		 3u5kB-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 0.92A 3u5kC-2l5eA:
17.0		 3u5kC-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 TRP A  57
PRO A  58
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 0.90A 3u5kC-2l5eA:
17.0		 3u5kC-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		7 / 8 TRP A  57
PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 0.93A 3u5kD-2l5eA:
16.8		 3u5kD-2l5eA:
77.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		4 / 5 LEU A  68
LEU A  70
ASN A 116
ILE A 122
 None
 0.88A 4a9jA-2l5eA:
17.0		 4a9jA-2l5eA:
77.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		4 / 5 LEU A  68
LEU A  70
ASN A 116
ILE A 122
 None
 0.78A 4a9jB-2l5eA:
17.4		 4a9jB-2l5eA:
77.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		4 / 5 LEU A  68
LEU A  70
ASN A 116
ILE A 122
 None
 0.70A 4a9jC-2l5eA:
16.0		 4a9jC-2l5eA:
77.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 9 TRP A  57
PRO A  58
GLN A  61
ASN A 116
ILE A 122
MET A 125
 None
 0.78A 4c66A-2l5eA:
17.5		 4c66A-2l5eA:
76.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		7 / 9 TRP A  57
PRO A  58
LEU A  68
LEU A  70
ASN A 116
ILE A 122
MET A 125
 None
 1.10A 4c66A-2l5eA:
17.5		 4c66A-2l5eA:
76.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 LEU A  68
LEU A  70
TYR A 115
ASN A 116
ASP A 120
ILE A 122
 None
 0.84A 4lzrA-2l5eA:
17.5		 4lzrA-2l5eA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 TRP A  57
LEU A  68
LEU A  70
TYR A 115
ASN A 116
ILE A 122
 None
 0.99A 4lzrA-2l5eA:
17.5		 4lzrA-2l5eA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		6 / 8 VAL A  63
LEU A  68
LEU A  70
TYR A 115
ASN A 116
ASP A 120
 None
 1.10A 4lzrA-2l5eA:
17.5		 4lzrA-2l5eA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		5 / 8 PRO A  58
CYH A 112
TYR A 115
ASN A 116
ILE A 122
 None
 0.77A 5y1yA-2l5eA:
17.1		 5y1yA-2l5eA:
77.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		4 / 8 PRO A  58
LEU A  68
LEU A  70
ASN A 116
 None
 0.71A 5y1yA-2l5eA:
17.1		 5y1yA-2l5eA:
77.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Mus
musculus) 		4 / 8 PRO A  58
LEU A  70
CYH A 112
ASN A 116
 None
 0.79A 5y1yA-2l5eA:
17.1		 5y1yA-2l5eA:
77.60