SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l5l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2l5l THIOREDOXIN
(Bacteroides
vulgatus) 		5 / 12 PRO A  52
VAL A  56
PHE A  98
ILE A  96
PHE A 117
 None
 1.33A 2v95A-2l5lA:
undetectable		 2v95A-2l5lA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 2l5l THIOREDOXIN
(Bacteroides
vulgatus) 		4 / 8 TYR A  24
PHE A  88
VAL A  43
LEU A  97
 None
 0.86A 2w98B-2l5lA:
undetectable		 2w98B-2l5lA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2l5l THIOREDOXIN
(Bacteroides
vulgatus) 		6 / 10 ILE A  96
LEU A  60
ILE A  71
ALA A  41
ILE A  73
ILE A  99
 None
 1.33A 5mvmD-2l5lA:
undetectable
5mvmE-2l5lA:
undetectable		 5mvmD-2l5lA:
18.94
5mvmE-2l5lA:
18.94