SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_B_ASDB1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2l5v	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 (Homo sapiens)	4 / 6	PHE A 377 LEU A 301 LEU A 361 ALA A 365	None	0.89A	2vcvB-2l5vA: undetectable	2vcvB-2l5vA: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_G_ASDG1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2l5v	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 (Homo sapiens)	4 / 7	PHE A 377 LEU A 301 LEU A 361 ALA A 365	None	0.97A	2vcvG-2l5vA: undetectable	2vcvG-2l5vA: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_K_ASDK1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2l5v	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 (Homo sapiens)	4 / 6	PHE A 377 LEU A 301 LEU A 361 ALA A 365	None	0.94A	2vcvK-2l5vA: undetectable	2vcvK-2l5vA: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_P_ASDP1224_1 (GLUTATHIONE S-TRANSFERASE A3)	2l5v	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 (Homo sapiens)	4 / 8	PHE A 377 LEU A 301 LEU A 361 ALA A 365	None	0.85A	2vcvP-2l5vA: undetectable	2vcvP-2l5vA: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	2l5v	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 (Homo sapiens)	4 / 4	SER A 290 ALA A 289 GLN A 337 THR A 332	None	1.48A	5n0sA-2l5vA: undetectable	5n0sA-2l5vA: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0W_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	2l5v	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 (Homo sapiens)	4 / 4	SER A 290 ALA A 289 GLN A 337 THR A 332	None	1.50A	5n0wA-2l5vA: undetectable	5n0wA-2l5vA: 15.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2VCV_B_ASDB1224_1","GLUTATHIONE S-TRANSFERASE A3","2l5v","PROTEASOMAL UBIQUITIN RECEPTOR ADRM1","Homo sapiens",4,"PHE A 377;LEU A 301;LEU A 361;ALA A 365","None","0.89A","2vcvB-2l5vA:undetectable","2vcvB-2l5vA:22.77"],["2VCV_G_ASDG1224_1","GLUTATHIONE S-TRANSFERASE A3","2l5v","PROTEASOMAL UBIQUITIN RECEPTOR ADRM1","Homo sapiens",4,"PHE A 377;LEU A 301;LEU A 361;ALA A 365","None","0.97A","2vcvG-2l5vA:undetectable","2vcvG-2l5vA:22.77"],["2VCV_K_ASDK1224_1","GLUTATHIONE S-TRANSFERASE A3","2l5v","PROTEASOMAL UBIQUITIN RECEPTOR ADRM1","Homo sapiens",4,"PHE A 377;LEU A 301;LEU A 361;ALA A 365","None","0.94A","2vcvK-2l5vA:undetectable","2vcvK-2l5vA:22.77"],["2VCV_P_ASDP1224_1","GLUTATHIONE S-TRANSFERASE A3","2l5v","PROTEASOMAL UBIQUITIN RECEPTOR ADRM1","Homo sapiens",4,"PHE A 377;LEU A 301;LEU A 361;ALA A 365","None","0.85A","2vcvP-2l5vA:undetectable","2vcvP-2l5vA:22.77"],["5N0S_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","2l5v","PROTEASOMAL UBIQUITIN RECEPTOR ADRM1","Homo sapiens",4,"SER A 290;ALA A 289;GLN A 337;THR A 332","None","1.48A","5n0sA-2l5vA:undetectable","5n0sA-2l5vA:16.27"],["5N0W_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","2l5v","PROTEASOMAL UBIQUITIN RECEPTOR ADRM1","Homo sapiens",4,"SER A 290;ALA A 289;GLN A 337;THR A 332","None","1.50A","5n0wA-2l5vA:undetectable","5n0wA-2l5vA:15.31"]]