SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 2l5y STROMAL INTERACTION
MOLECULE 2
(Homo
sapiens) 		3 / 3 GLU A  90
HIS A 113
HIS A 118
 None
 0.94A 3co4A-2l5yA:
undetectable		 3co4A-2l5yA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 2l5y STROMAL INTERACTION
MOLECULE 2
(Homo
sapiens) 		4 / 8 ARG A 127
LEU A 124
MET A  79
HIS A 113
 None
 1.50A 3zmdA-2l5yA:
undetectable
3zmdB-2l5yA:
undetectable		 3zmdA-2l5yA:
25.58
3zmdB-2l5yA:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2l5y STROMAL INTERACTION
MOLECULE 2
(Homo
sapiens) 		4 / 8 ILE A 121
SER A  92
LEU A 203
LEU A 199
 None
 0.92A 4xtaB-2l5yA:
undetectable		 4xtaB-2l5yA:
21.11