SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 2l6h FOCAL ADHESION
KINASE 1, LINKER,
PAXILLIN
(Gallus
gallus;
unidentified) 		5 / 9 GLY A  48
GLU A  46
LEU A  87
LEU A  84
ILE A  88
 None
 1.42A 3nbqA-2l6hA:
undetectable		 3nbqA-2l6hA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2l6h FOCAL ADHESION
KINASE 1, LINKER,
PAXILLIN
(Gallus
gallus;
unidentified) 		5 / 10 ALA A 121
LEU A 125
LEU A  21
LEU A  51
ALA A  50
 None
 1.10A 4zbrA-2l6hA:
5.0		 4zbrA-2l6hA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2l6h FOCAL ADHESION
KINASE 1, LINKER,
PAXILLIN
(Gallus
gallus;
unidentified) 		5 / 12 SER A  68
ASN A  11
VAL A  14
VAL A 127
LEU A 125
 None
 1.04A 5kocA-2l6hA:
undetectable		 5kocA-2l6hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2l6h FOCAL ADHESION
KINASE 1, LINKER,
PAXILLIN
(Gallus
gallus;
unidentified) 		5 / 12 SER A  68
ASN A  11
VAL A  14
VAL A 127
LEU A 125
 None
 1.05A 5kocB-2l6hA:
undetectable		 5kocB-2l6hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 2l6h FOCAL ADHESION
KINASE 1, LINKER,
PAXILLIN
(Gallus
gallus;
unidentified) 		5 / 12 VAL A  64
LEU A  65
ILE A  73
VAL A  14
LEU A 125
 None
 0.97A 6ajiA-2l6hA:
undetectable		 6ajiA-2l6hA:
12.27