SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 2l6l DNAJ HOMOLOG
SUBFAMILY C MEMBER
24
(Homo
sapiens) 		4 / 5 HIS A 147
GLU A 129
SER A 110
HIS A 109
 None
 1.42A 1errA-2l6lA:
undetectable
1errB-2l6lA:
undetectable		 1errA-2l6lA:
18.94
1errB-2l6lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 2l6l DNAJ HOMOLOG
SUBFAMILY C MEMBER
24
(Homo
sapiens) 		3 / 3 ARG A  76
GLU A 127
ASP A 108
 None
 0.94A 3g2oA-2l6lA:
undetectable		 3g2oA-2l6lA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 2l6l DNAJ HOMOLOG
SUBFAMILY C MEMBER
24
(Homo
sapiens) 		3 / 3 GLY A 119
CYH A 117
CYH A 115
 None
ZN  A 201 (-2.2A)
ZN  A 201 (-2.2A)
 0.83A 5inzB-2l6lA:
undetectable		 5inzB-2l6lA:
11.32