SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l6x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_B_IPBB600_0 (ODORANT-BINDING PROTEIN)	2l6x	GREEN-LIGHT ABSORBING PROTEORHODOPSIN (uncultured marine gamma proteobacterium EBAC31A08)	4 / 4	ILE A 194 MET A 189 VAL A 102 GLY A 196	None	1.43A	1e06B-2l6xA: undetectable	1e06B-2l6xA: 19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J96_A_TESA903_1 (3ALPHA-HYDROXYSTEROI D DEHYDROGENASE TYPE 3)	2l6x	GREEN-LIGHT ABSORBING PROTEORHODOPSIN (uncultured marine gamma proteobacterium EBAC31A08)	4 / 6	TYR A 110 VAL A 241 ILE A 237 LEU A 105	None	1.20A	1j96A-2l6xA: undetectable	1j96A-2l6xA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PW7_C_RABC647_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	2l6x	GREEN-LIGHT ABSORBING PROTEORHODOPSIN (uncultured marine gamma proteobacterium EBAC31A08)	5 / 9	SER A 246 VAL A 241 GLU A 245 SER A 55 ILE A 238	None	1.30A	1pw7C-2l6xA: undetectable	1pw7C-2l6xA: 22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_C_SUEC1201_2 (NS3 PROTEASE, NS4A PROTEIN)	2l6x	GREEN-LIGHT ABSORBING PROTEORHODOPSIN (uncultured marine gamma proteobacterium EBAC31A08)	4 / 5	TYR A 204 ILE A 232 LEU A 233 LYS A 231	None None None RET A 301 (-1.3A)	1.11A	3sueC-2l6xA: undetectable	3sueC-2l6xA: 18.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E06_B_IPBB600_0","ODORANT-BINDING PROTEIN","2l6x","GREEN-LIGHT ABSORBING PROTEORHODOPSIN","uncultured marine gamma proteobacterium EBAC31A08",4,"ILE A 194;MET A 189;VAL A 102;GLY A 196","None","1.43A","1e06B-2l6xA:undetectable","1e06B-2l6xA:19.15"],["1J96_A_TESA903_1","3ALPHA-HYDROXYSTEROID DEHYDROGENASE TYPE 3","2l6x","GREEN-LIGHT ABSORBING PROTEORHODOPSIN","uncultured marine gamma proteobacterium EBAC31A08",4,"TYR A 110;VAL A 241;ILE A 237;LEU A 105","None","1.20A","1j96A-2l6xA:undetectable","1j96A-2l6xA:20.99"],["1PW7_C_RABC647_1","PURINE NUCLEOSIDE PHOSPHORYLASE","2l6x","GREEN-LIGHT ABSORBING PROTEORHODOPSIN","uncultured marine gamma proteobacterium EBAC31A08",5,"SER A 246;VAL A 241;GLU A 245;SER A  55;ILE A 238","None","1.30A","1pw7C-2l6xA:undetectable","1pw7C-2l6xA:22.43"],["3SUE_C_SUEC1201_2","NS3 PROTEASE, NS4A PROTEIN","2l6x","GREEN-LIGHT ABSORBING PROTEORHODOPSIN","uncultured marine gamma proteobacterium EBAC31A08",4,"TYR A 204;ILE A 232;LEU A 233;LYS A 231","None;None;None;RET A 301 (-1.3A)","1.11A","3sueC-2l6xA:undetectable","3sueC-2l6xA:18.97"]]