SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l6z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JST_A_HLTA101_1 (FOUR-ALPHA-HELIX BUNDLE)	2l6z	LIM DOMAIN ONLY 2, LINKER, LIM DOMAIN-BINDING PROTEIN 1 (Mus musculus)	4 / 5	TRP C 151 ALA C 124 LEU C 136 ALA C 123	None ZN C 181 ( 4.4A) None None	1.26A	2jstA-2l6zC: undetectable 2jstB-2l6zC: undetectable	2jstA-2l6zC: 19.09 2jstB-2l6zC: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D41_A_FCNA4001_1 (FOMA PROTEIN)	2l6z	LIM DOMAIN ONLY 2, LINKER, LIM DOMAIN-BINDING PROTEIN 1 (Mus musculus)	4 / 8	GLY C 166 GLY C 165 GLY C 159 THR C 152	None	0.70A	3d41A-2l6zC: undetectable	3d41A-2l6zC: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZT_A_SAMA1472_1 (METHYLTRANSFERASE WBDD)	2l6z	LIM DOMAIN ONLY 2, LINKER, LIM DOMAIN-BINDING PROTEIN 1 (Mus musculus)	3 / 3	GLN C 126 ASP C 147 GLN C 146	None ZN C 181 (-2.4A) ZN C 181 ( 4.9A)	0.86A	4aztA-2l6zC: undetectable	4aztA-2l6zC: 10.87