SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2l73 NADPH OXIDASE
ORGANIZER 1
(Homo
sapiens) 		4 / 5 PHE A 119
PHE A 118
PHE A  45
VAL A  10
 None
 1.19A 2lh6A-2l73A:
undetectable		 2lh6A-2l73A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 2l73 NADPH OXIDASE
ORGANIZER 1
(Homo
sapiens) 		5 / 9 LEU A 103
LEU A  48
VAL A  38
VAL A  28
PHE A  26
 None
 1.20A 4wnvB-2l73A:
0.0		 4wnvB-2l73A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2l73 NADPH OXIDASE
ORGANIZER 1
(Homo
sapiens) 		5 / 12 VAL A  10
ASP A 125
SER A  99
GLN A  22
LEU A  92
 None
 1.19A 5syfB-2l73A:
undetectable		 5syfB-2l73A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 2l73 NADPH OXIDASE
ORGANIZER 1
(Homo
sapiens) 		3 / 3 ALA A  90
PHE A  24
GLN A  22
 None
 0.84A 6eceA-2l73A:
undetectable		 6eceA-2l73A:
20.60