SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 2l7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  51
ILE A  11
ILE A   9
THR A  68
 None
 0.98A 1sbrB-2l7eA:
undetectable		 1sbrB-2l7eA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2l7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		4 / 7 VAL A  37
ILE A  36
LEU A 105
LEU A  86
 None
 0.90A 4xo7A-2l7eA:
undetectable		 4xo7A-2l7eA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2l7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  55
ARG A  10
LEU A  39
ILE A   9
 None
 0.91A 4xtaB-2l7eA:
undetectable		 4xtaB-2l7eA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2l7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 123
GLN A 119
ILE A 120
GLY A  97
 None
 0.98A 5nzyA-2l7eA:
undetectable		 5nzyA-2l7eA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2l7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14
(Saccharomyces
cerevisiae) 		5 / 10 HIS A  57
ILE A  55
ILE A   9
ILE A 118
LEU A  92
 None
 1.43A 5vkqC-2l7eA:
undetectable
5vkqD-2l7eA:
undetectable		 5vkqC-2l7eA:
6.05
5vkqD-2l7eA:
6.05