SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
2l89 PWWP
DOMAIN-CONTAINING
PROTEIN 1

(Schizosaccharomy
ces
pombe)
5 / 12 PHE A  94
VAL A  58
PHE A 119
LEU A 120
ILE A 116
None
1.16A 5b8iC-2l89A:
undetectable
5b8iC-2l89A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
2l89 PWWP
DOMAIN-CONTAINING
PROTEIN 1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A  95
LEU A  71
GLY A  53
ASP A 142
None
0.95A 5ik1A-2l89A:
undetectable
5ik1A-2l89A:
14.74