SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 2l90 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Mus
musculus) 		4 / 8 TYR A 200
TYR A 160
ARG A 194
VAL A  67
 None
None
MYR  A  21 ( 3.5A)
None
 0.69A 2fl5E-2l90A:
undetectable
2fl5F-2l90A:
undetectable		 2fl5E-2l90A:
22.96
2fl5F-2l90A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2l90 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Mus
musculus) 		4 / 8 THR A 111
GLN A 154
SER A 108
CYH A 107
 None
 1.22A 2xz5C-2l90A:
undetectable
2xz5D-2l90A:
undetectable		 2xz5C-2l90A:
21.79
2xz5D-2l90A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 2l90 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Mus
musculus) 		3 / 3 LEU A 171
GLU A 175
SER A 173
 None
 0.83A 4ccqA-2l90A:
undetectable		 4ccqA-2l90A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 2l90 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Mus
musculus) 		4 / 4 HIS A  48
LEU A 131
TYR A 121
GLY A  85
 None
 1.33A 6n91A-2l90A:
undetectable		 6n91A-2l90A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 2l90 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Mus
musculus) 		4 / 4 HIS A  48
LEU A 131
TYR A 121
GLY A  85
 None
 1.33A 6n91B-2l90A:
undetectable		 6n91B-2l90A:
15.79