SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 2l9b MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 195
TRP A 187
PHE A 184
GLU A 186
 None
 1.10A 1dmiA-2l9bA:
undetectable
1dmiB-2l9bA:
undetectable		 1dmiA-2l9bA:
13.86
1dmiB-2l9bA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2l9b MRNA
3'-END-PROCESSING
PROTEIN RNA14
MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 7 VAL B 635
LEU A 205
THR A 209
LEU A 212
 None
 0.53A 1jgsA-2l9bB:
undetectable		 1jgsA-2l9bB:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 2l9b MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 6 THR A 209
PHE A 207
LEU A 227
LEU A 224
 None
 1.09A 3bgdA-2l9bA:
undetectable		 3bgdA-2l9bA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 2l9b MRNA
3'-END-PROCESSING
PROTEIN RNA15
MRNA
3'-END-PROCESSING
PROTEIN RNA14
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 ILE A 165
VAL A 154
LEU A 169
THR A 159
LEU B 638
 None
 1.15A 6b54A-2l9bA:
undetectable		 6b54A-2l9bA:
16.21