SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_B_SPMB1433_1
(NITROALKANE OXIDASE)		 2l9f CALE8
(Micromonospora
echinospora) 		5 / 11 VAL A  55
ALA A  59
MET A  62
LEU A  22
VAL A  23
 None
 1.42A 2c12B-2l9fA:
undetectable		 2c12B-2l9fA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_D_SPMD1434_1
(NITROALKANE OXIDASE)		 2l9f CALE8
(Micromonospora
echinospora) 		5 / 10 VAL A  55
ALA A  59
MET A  62
LEU A  22
VAL A  23
 None
 1.41A 2c12D-2l9fA:
undetectable		 2c12D-2l9fA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2l9f CALE8
(Micromonospora
echinospora) 		4 / 5 LEU A  85
PHE A  73
VAL A  67
ALA A  59
 None
 1.15A 2cizA-2l9fA:
undetectable		 2cizA-2l9fA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2l9f CALE8
(Micromonospora
echinospora) 		3 / 3 MET A  46
GLU A  25
ARG A  26
 None
 1.01A 5tjyA-2l9fA:
undetectable		 5tjyA-2l9fA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2l9f CALE8
(Micromonospora
echinospora) 		3 / 3 MET A  46
GLU A  25
ARG A  26
 None
 1.06A 5tjzA-2l9fA:
undetectable		 5tjzA-2l9fA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2l9f CALE8
(Micromonospora
echinospora) 		3 / 3 HIS A 100
HIS A  98
ARG A  60
 None
 0.99A 6b58A-2l9fA:
undetectable		 6b58A-2l9fA:
11.80