SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2l9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 2l9j MATRIX PROTEIN 2-1
(Human
orthopneumovirus) 		4 / 7 SER A 137
ILE A 111
ILE A 135
THR A 145
 None
 1.00A 1sbrB-2l9jA:
undetectable		 1sbrB-2l9jA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2l9j MATRIX PROTEIN 2-1
(Human
orthopneumovirus) 		3 / 3 LEU A 152
PRO A 153
ARG A 126
 None
 0.69A 4klrB-2l9jA:
undetectable		 4klrB-2l9jA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2l9j MATRIX PROTEIN 2-1
(Human
orthopneumovirus) 		4 / 7 ILE A 135
LEU A 103
MET A  99
LEU A 102
 None
 0.96A 5u4sA-2l9jA:
undetectable		 5u4sA-2l9jA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2l9j MATRIX PROTEIN 2-1
(Human
orthopneumovirus) 		4 / 8 ILE A 135
LEU A 103
MET A  99
LEU A 102
 None
 0.93A 5u4sB-2l9jA:
undetectable		 5u4sB-2l9jA:
16.87