SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2la6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2la6 RNA-BINDING PROTEIN
FUS
(Homo
sapiens) 		5 / 9 PHE A  70
VAL A  30
ILE A  93
VAL A  95
ILE A  16
 None
 1.29A 1gebA-2la6A:
undetectable		 1gebA-2la6A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 2la6 RNA-BINDING PROTEIN
FUS
(Homo
sapiens) 		3 / 3 GLY A  20
GLU A  65
ASN A  91
 None
 0.48A 1zq9A-2la6A:
undetectable		 1zq9A-2la6A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2la6 RNA-BINDING PROTEIN
FUS
(Homo
sapiens) 		4 / 5 LEU A  62
THR A  55
THR A  59
GLY A  60
 None
 1.22A 6gtqA-2la6A:
undetectable		 6gtqA-2la6A:
19.54