SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2lab BETA/ALPHA-AMYLASE
(Paenibacillus
polymyxa) 		5 / 9 GLY A 633
ALA A 569
ILE A 571
GLY A 629
THR A 614
 None
 1.21A 1c9sQ-2labA:
undetectable
1c9sR-2labA:
undetectable		 1c9sQ-2labA:
22.00
1c9sR-2labA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 2lab BETA/ALPHA-AMYLASE
(Paenibacillus
polymyxa) 		5 / 12 MET A 566
ILE A 549
ILE A 626
PHE A 591
LEU A 587
 None
 1.17A 5tiwB-2labA:
undetectable		 5tiwB-2labA:
13.94