SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AMU_A_AG2A422_1 (PUTATIVE UNCHARACTERIZED PROTEIN)	2lbc	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 (Homo sapiens)	4 / 5	GLU A 18 VAL A 24 CYH A 20 ARG A 21	None	1.25A	3amuA-2lbcA: 0.0	3amuA-2lbcA: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NMU_F_SAMF228_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE NOP5/NOP56 RELATED PROTEIN)	2lbc	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 (Homo sapiens)	5 / 12	GLY A 31 GLU A 33 PHE A 36 ALA A 35 ASP A 3	None	1.35A	3nmuA-2lbcA: undetectable 3nmuF-2lbcA: undetectable	3nmuA-2lbcA: 15.74 3nmuF-2lbcA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AGG_Z_AG2Z503_0 (TRNA(ILE2) 2-AGMATINYLCYTIDINE SYNTHETASE TIAS)	2lbc	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 (Homo sapiens)	4 / 5	GLU A 18 VAL A 24 CYH A 20 ARG A 21	None	1.36A	6aggZ-2lbcA: 0.0	6aggZ-2lbcA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6S_A_CXQA507_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN,GP1 ENVELOPE GLYCOPROTEIN)	2lbc	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13 (Homo sapiens)	4 / 5	ARG A 100 ALA A 101 GLN A 97 ILE A 113	None	1.14A	6f6sA-2lbcA: undetectable 6f6sB-2lbcA: undetectable	6f6sA-2lbcA: 19.08 6f6sB-2lbcA: 24.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3AMU_A_AG2A422_1","PUTATIVE UNCHARACTERIZED PROTEIN","2lbc","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13","Homo sapiens",4,"GLU A  18;VAL A  24;CYH A  20;ARG A  21","None","1.25A","3amuA-2lbcA:0.0","3amuA-2lbcA:16.26"],["3NMU_F_SAMF228_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE;NOP5\/NOP56 RELATED PROTEIN","2lbc","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13","Homo sapiens",5,"GLY A  31;GLU A  33;PHE A  36;ALA A  35;ASP A   3","None","1.35A","3nmuA-2lbcA:undetectable;3nmuF-2lbcA:undetectable","3nmuA-2lbcA:15.74;3nmuF-2lbcA:20.09"],["6AGG_Z_AG2Z503_0","TRNA(ILE2) 2-AGMATINYLCYTIDINE SYNTHETASE TIAS","2lbc","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13","Homo sapiens",4,"GLU A  18;VAL A  24;CYH A  20;ARG A  21","None","1.36A","6aggZ-2lbcA:0.0","6aggZ-2lbcA:19.17"],["6F6S_A_CXQA507_1","ENVELOPE GLYCOPROTEIN,ENVELOPE GLYCOPROTEIN,GP1;ENVELOPE GLYCOPROTEIN","2lbc","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 13","Homo sapiens",4,"ARG A 100;ALA A 101;GLN A  97;ILE A 113","None","1.14A","6f6sA-2lbcA:undetectable;6f6sB-2lbcA:undetectable","6f6sA-2lbcA:19.08;6f6sB-2lbcA:24.32"]]