SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lc4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2lc4 PILP PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLY A  63
ILE A  80
VAL A  79
 None
 0.50A 3nv6A-2lc4A:
undetectable		 3nv6A-2lc4A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2lc4 PILP PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  97
LEU A  62
GLY A  63
GLY A  67
 None
 0.66A 3si7C-2lc4A:
undetectable
3si7D-2lc4A:
undetectable		 3si7C-2lc4A:
18.88
3si7D-2lc4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2lc4 PILP PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A  65
LEU A  97
PHE A  26
 None
 0.71A 5dsgA-2lc4A:
undetectable		 5dsgA-2lc4A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2lc4 PILP PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 110
HIS A 111
ARG A  64
 None
 1.07A 6b58A-2lc4A:
undetectable		 6b58A-2lc4A:
12.84