SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2lck MITOCHONDRIAL
UNCOUPLING PROTEIN 2
(Mus
musculus) 		6 / 12 LYS A 109
GLY A 117
GLY A 115
SER A 111
ALA A 122
LEU A 121
 None
 1.47A 5kpcA-2lckA:
undetectable		 5kpcA-2lckA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2lck MITOCHONDRIAL
UNCOUPLING PROTEIN 2
(Mus
musculus) 		3 / 3 MET A  90
GLN A  89
ARG A  88
 None
 1.11A 5m36A-2lckA:
2.3		 5m36A-2lckA:
20.25