SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2lcq PUTATIVE TOXIN VAPC6
(Pyrococcus
horikoshii) 		4 / 8 SER A  13
GLU A  84
ILE A 106
ALA A  69
 None
 0.95A 3aodA-2lcqA:
undetectable		 3aodA-2lcqA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2lcq PUTATIVE TOXIN VAPC6
(Pyrococcus
horikoshii) 		5 / 11 THR A  72
VAL A  68
ILE A  65
ASN A 102
ILE A 106
 None
 1.20A 3kpcA-2lcqA:
undetectable		 3kpcA-2lcqA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 2lcq PUTATIVE TOXIN VAPC6
(Pyrococcus
horikoshii) 		4 / 8 TYR A  90
ALA A  69
THR A  72
LEU A 109
 None
 0.93A 3l4dA-2lcqA:
undetectable		 3l4dA-2lcqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2lcq PUTATIVE TOXIN VAPC6
(Pyrococcus
horikoshii) 		4 / 6 THR A   8
GLY A  24
ILE A  22
LEU A   5
 None
 0.92A 4acbC-2lcqA:
undetectable		 4acbC-2lcqA:
19.19