SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ld4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		3 / 3 GLU A 133
GLU A 129
LEU A  95
 None
 0.61A 1v8bA-2ld4A:
2.8		 1v8bA-2ld4A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		3 / 3 GLU A 133
GLU A 129
LEU A  95
 None
 0.61A 1v8bB-2ld4A:
2.7		 1v8bB-2ld4A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 11 LEU A  67
GLY A  66
ILE A  47
PRO A  98
LYS A 114
 None
 1.24A 3bjwB-2ld4A:
undetectable		 3bjwB-2ld4A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 12 LEU A  67
GLY A  66
ILE A  47
PRO A  98
LYS A 114
 None
 1.24A 3bjwF-2ld4A:
undetectable		 3bjwF-2ld4A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 11 LEU A  67
GLY A  66
ILE A  47
PRO A  98
LYS A 114
 None
 1.19A 3bjwH-2ld4A:
undetectable		 3bjwH-2ld4A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 12 ALA A  13
ARG A  85
LEU A  87
SER A 122
LEU A 124
 None
 1.15A 3k2hB-2ld4A:
undetectable		 3k2hB-2ld4A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 10 LEU A 119
ALA A  84
ILE A  62
VAL A 127
LEU A 124
 None
 0.92A 3ogpB-2ld4A:
undetectable		 3ogpB-2ld4A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 10 LEU A 119
ALA A  84
ILE A  62
VAL A 127
LEU A 124
 None
 0.91A 3ogpA-2ld4A:
undetectable		 3ogpA-2ld4A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		6 / 12 GLY A  37
GLY A  40
GLY A   9
SER A   7
VAL A  42
VAL A  14
 None
 1.43A 4htfB-2ld4A:
8.5		 4htfB-2ld4A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		6 / 12 GLY A  37
GLY A  40
GLY A   9
SER A   7
VAL A  42
VAL A  29
 None
 1.34A 4htfB-2ld4A:
8.5		 4htfB-2ld4A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2ld4 ANAMORSIN
(Homo
sapiens) 		6 / 12 GLY A  37
GLY A  40
LEU A  35
SER A   7
VAL A  42
VAL A  29
 None
 1.39A 4htfB-2ld4A:
8.5		 4htfB-2ld4A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_C_QI9C602_0
(CYTOCHROME P450 2D6)		 2ld4 ANAMORSIN
(Homo
sapiens) 		5 / 9 LEU A  67
ASP A   3
THR A  36
VAL A  42
VAL A  14
 None
 1.28A 4wnvC-2ld4A:
0.0		 4wnvC-2ld4A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2ld4 ANAMORSIN
(Homo
sapiens) 		3 / 3 LYS A  56
ILE A  86
ILE A  63
 None
 0.66A 4y0qA-2ld4A:
undetectable		 4y0qA-2ld4A:
21.35