SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 2lem APOLIPOPROTEIN A-I
(Mus
musculus) 		5 / 11 HIS A 165
LEU A 162
ARG A  26
GLY A  25
LYS A  22
 None
 1.39A 2bxmA-2lemA:
2.3		 2bxmA-2lemA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 2lem APOLIPOPROTEIN A-I
(Mus
musculus) 		4 / 6 HIS A 165
ARG A  26
GLY A  25
LYS A  22
 None
 1.24A 2i30A-2lemA:
2.8		 2i30A-2lemA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2lem APOLIPOPROTEIN A-I
(Mus
musculus) 		4 / 4 GLN A  97
PRO A  98
VAL A  96
GLU A 102
 None
 0.98A 3huoA-2lemA:
undetectable		 3huoA-2lemA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2lem APOLIPOPROTEIN A-I
(Mus
musculus) 		4 / 7 SER A 172
LEU A 208
HIS A 196
SER A  24
 None
 0.93A 3r9vA-2lemA:
4.6
3r9vB-2lemA:
3.8		 3r9vA-2lemA:
21.93
3r9vB-2lemA:
21.93