SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H4O_B_BEZB1162_0 (PEROXIREDOXIN 5)	2lex	PROBABLE WRKY TRANSCRIPTION FACTOR 4 (Arabidopsis thaliana)	4 / 8	THR A 436 PRO A 437 GLY A 438 CYH A 439	ZN A 500 (-3.5A) None None ZN A 500 (-2.5A)	0.64A	1h4oB-2lexA: undetectable	1h4oB-2lexA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H4O_G_BEZG1162_0 (PEROXIREDOXIN 5)	2lex	PROBABLE WRKY TRANSCRIPTION FACTOR 4 (Arabidopsis thaliana)	4 / 8	THR A 436 PRO A 437 GLY A 438 CYH A 439	ZN A 500 (-3.5A) None None ZN A 500 (-2.5A)	0.66A	1h4oG-2lexA: undetectable	1h4oG-2lexA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OC3_A_BEZA201_0 (PEROXIREDOXIN 5)	2lex	PROBABLE WRKY TRANSCRIPTION FACTOR 4 (Arabidopsis thaliana)	4 / 8	THR A 436 PRO A 437 GLY A 438 CYH A 439	ZN A 500 (-3.5A) None None ZN A 500 (-2.5A)	0.62A	1oc3A-2lexA: undetectable	1oc3A-2lexA: 18.82