SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lez'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2lez SECRETED EFFECTOR
PROTEIN PIPB2
(Salmonella
enterica) 		5 / 12 TYR A  36
LEU A  82
PHE A  40
PHE A  92
ILE A  80
 None
 1.28A 1xosA-2lezA:
undetectable		 1xosA-2lezA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2lez SECRETED EFFECTOR
PROTEIN PIPB2
(Salmonella
enterica) 		4 / 8 PHE A 124
MET A  61
THR A  60
LEU A  57
 None
 0.90A 3abkA-2lezA:
undetectable
3abkJ-2lezA:
undetectable		 3abkA-2lezA:
13.68
3abkJ-2lezA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2lez SECRETED EFFECTOR
PROTEIN PIPB2
(Salmonella
enterica) 		4 / 8 PHE A 124
MET A  61
THR A  60
LEU A  57
 None
 0.92A 3abmN-2lezA:
undetectable
3abmW-2lezA:
undetectable		 3abmN-2lezA:
13.68
3abmW-2lezA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lez SECRETED EFFECTOR
PROTEIN PIPB2
(Salmonella
enterica) 		4 / 7 PHE A 124
MET A  61
THR A  60
LEU A  57
 None
 0.93A 5b3sN-2lezA:
undetectable
5b3sW-2lezA:
undetectable		 5b3sN-2lezA:
13.68
5b3sW-2lezA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lez SECRETED EFFECTOR
PROTEIN PIPB2
(Salmonella
enterica) 		4 / 7 PHE A 124
MET A  61
THR A  60
LEU A  57
 None
 0.91A 5iy5N-2lezA:
undetectable
5iy5W-2lezA:
undetectable		 5iy5N-2lezA:
13.68
5iy5W-2lezA:
16.55