SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 2lf2 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 8 PHE A  92
GLY A  62
PHE A  35
PHE A 118
 None
 0.98A 3ko0B-2lf2A:
undetectable
3ko0J-2lf2A:
undetectable		 3ko0B-2lf2A:
22.49
3ko0J-2lf2A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 2lf2 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 7 PHE A  92
GLY A  62
PHE A  35
PHE A 118
 None
 1.06A 3ko0K-2lf2A:
undetectable
3ko0S-2lf2A:
undetectable		 3ko0K-2lf2A:
22.49
3ko0S-2lf2A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 2lf2 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 6 PRO A 110
LEU A 105
ASN A 106
GLU A 108
 None
 0.74A 3zqtA-2lf2A:
undetectable		 3zqtA-2lf2A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 2lf2 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		3 / 3 ASP A  96
TRP A  44
SER A  79
 None
 0.90A 4lrhA-2lf2A:
undetectable		 4lrhA-2lf2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2lf2 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 6 ILE A  18
LYS A  13
LEU A 139
GLU A 140
 None
 0.95A 4w5nA-2lf2A:
undetectable		 4w5nA-2lf2A:
13.19