SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lf3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 2lf3 EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 VAL A 354
GLY A 355
ALA A 315
LEU A 319
 None
 0.60A 1e7bB-2lf3A:
undetectable		 1e7bB-2lf3A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 2lf3 EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 LEU A 333
VAL A 354
GLY A 355
ALA A 315
LEU A 319
 None
 1.11A 2bxgA-2lf3A:
undetectable		 2bxgA-2lf3A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2lf3 EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 LEU A 372
PRO A 371
LEU A 375
 None
 0.62A 2po5B-2lf3A:
undetectable		 2po5B-2lf3A:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 2lf3 EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 318
ILE A 324
ILE A 343
PRO A 344
ILE A 356
 None
 1.22A 3clbB-2lf3A:
undetectable		 3clbB-2lf3A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2lf3 EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ILE A 347
ALA A 350
ALA A 320
LEU A 329
LEU A 379
 None
 1.13A 3uvvA-2lf3A:
undetectable		 3uvvA-2lf3A:
16.67