SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lgh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		5 / 11 LEU A  79
LEU A 125
LEU A  45
ILE A   9
ILE A  26
 None
 1.13A 2uxoB-2lghA:
undetectable		 2uxoB-2lghA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		5 / 12 PHE A  81
THR A  71
ILE A 124
ILE A   3
ALA A 108
 None
 1.16A 3nxuB-2lghA:
undetectable		 3nxuB-2lghA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		5 / 12 ILE A   9
PHE A  93
VAL A  43
LEU A  45
PHE A  51
 None
 1.07A 3w67B-2lghA:
undetectable		 3w67B-2lghA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		5 / 12 ILE A   9
PHE A  93
LEU A  45
PHE A  51
VAL A  73
 None
 1.07A 3w67C-2lghA:
undetectable		 3w67C-2lghA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		4 / 8 GLY A  68
TRP A 121
GLN A 117
ASP A  85
 None
 0.81A 5vlmA-2lghA:
undetectable		 5vlmA-2lghA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		4 / 8 GLY A  68
TRP A 121
GLN A 117
ASP A  85
 None
 1.04A 5vlmD-2lghA:
undetectable		 5vlmD-2lghA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 2lgh UNCHARACTERIZED
PROTEIN
(Aeromonas
hydrophila) 		4 / 7 GLY A  68
TRP A 121
GLN A 117
ASP A  85
 None
 0.98A 5vlmG-2lghA:
undetectable		 5vlmG-2lghA:
22.11