SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XNR_A_ACTA1001_0 (NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3)	2lhf	OUTER MEMBRANE PROTEIN H1 (Pseudomonas aeruginosa)	3 / 3	SER A 168 ARG A 142 GLN A 170	None	0.93A	2xnrA-2lhfA: undetectable	2xnrA-2lhfA: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KR4_C_AICC401_1 (OUTER MEMBRANE PROTEIN F)	2lhf	OUTER MEMBRANE PROTEIN H1 (Pseudomonas aeruginosa)	4 / 8	ARG A 54 TYR A 56 ARG A 45 GLU A 130	None	0.98A	4kr4C-2lhfA: undetectable	4kr4C-2lhfA: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5N_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	2lhf	OUTER MEMBRANE PROTEIN H1 (Pseudomonas aeruginosa)	4 / 4	TYR A 172 THR A 9 GLY A 174 LEU A 128	None	1.34A	4w5nA-2lhfA: undetectable	4w5nA-2lhfA: 11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_A_7V7A202_1 (ENDO-1,4-BETA-XYLANA SE A)	2lhf	OUTER MEMBRANE PROTEIN H1 (Pseudomonas aeruginosa)	5 / 12	PHE A 179 VAL A 6 ALA A 57 ALA A 46 GLY A 47	None	1.24A	5tzoA-2lhfA: undetectable	5tzoA-2lhfA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_C_7V7C201_1 (ENDO-1,4-BETA-XYLANA SE A)	2lhf	OUTER MEMBRANE PROTEIN H1 (Pseudomonas aeruginosa)	5 / 12	PHE A 179 VAL A 6 ALA A 57 ALA A 46 GLY A 47	None	1.25A	5tzoC-2lhfA: undetectable	5tzoC-2lhfA: 20.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XNR_A_ACTA1001_0","NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3","2lhf","OUTER MEMBRANE PROTEIN H1","Pseudomonas aeruginosa",3,"SER A 168;ARG A 142;GLN A 170","None","0.93A","2xnrA-2lhfA:undetectable","2xnrA-2lhfA:22.65"],["4KR4_C_AICC401_1","OUTER MEMBRANE PROTEIN F","2lhf","OUTER MEMBRANE PROTEIN H1","Pseudomonas aeruginosa",4,"ARG A  54;TYR A  56;ARG A  45;GLU A 130","None","0.98A","4kr4C-2lhfA:undetectable","4kr4C-2lhfA:20.35"],["4W5N_A_IPHA903_0","PROTEIN ARGONAUTE-2","2lhf","OUTER MEMBRANE PROTEIN H1","Pseudomonas aeruginosa",4,"TYR A 172;THR A   9;GLY A 174;LEU A 128","None","1.34A","4w5nA-2lhfA:undetectable","4w5nA-2lhfA:11.42"],["5TZO_A_7V7A202_1","ENDO-1,4-BETA-XYLANASE A","2lhf","OUTER MEMBRANE PROTEIN H1","Pseudomonas aeruginosa",5,"PHE A 179;VAL A   6;ALA A  57;ALA A  46;GLY A  47","None","1.24A","5tzoA-2lhfA:undetectable","5tzoA-2lhfA:20.20"],["5TZO_C_7V7C201_1","ENDO-1,4-BETA-XYLANASE A","2lhf","OUTER MEMBRANE PROTEIN H1","Pseudomonas aeruginosa",5,"PHE A 179;VAL A   6;ALA A  57;ALA A  46;GLY A  47","None","1.25A","5tzoC-2lhfA:undetectable","5tzoC-2lhfA:20.20"]]