SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ljp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.84A 1a7yB-2ljpA:
undetectable		 1a7yB-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.90A 1dscC-2ljpA:
undetectable		 1dscC-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.75A 1dscC-2ljpA:
undetectable		 1dscC-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.89A 1fjaC-2ljpA:
undetectable		 1fjaC-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.89A 1fjaD-2ljpA:
undetectable		 1fjaD-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.85A 1i3wG-2ljpA:
undetectable		 1i3wG-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.85A 1i3wH-2ljpA:
undetectable		 1i3wH-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.85A 1mnvD-2ljpA:
undetectable		 1mnvD-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.81A 1mnvD-2ljpA:
undetectable		 1mnvD-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.84A 1qfiA-2ljpA:
undetectable		 1qfiA-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.87A 1unjL-2ljpA:
undetectable		 1unjL-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.80A 1unjL-2ljpA:
undetectable		 1unjL-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.80A 1unjR-2ljpA:
undetectable		 1unjR-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.81A 1unjR-2ljpA:
undetectable		 1unjR-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.83A 1unjW-2ljpA:
undetectable		 1unjW-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.81A 1unjX-2ljpA:
undetectable		 1unjX-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.81A 1unjX-2ljpA:
undetectable		 1unjX-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.84A 1unmE-2ljpA:
undetectable		 1unmE-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  34
PRO A  31
THR A  30
 None
 0.84A 1unmF-2ljpA:
undetectable		 1unmF-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 THR A  30
THR A  34
PRO A  31
 None
 0.83A 1unmF-2ljpA:
undetectable		 1unmF-2ljpA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2ljp RIBONUCLEASE P
PROTEIN COMPONENT
(Escherichia
coli) 		3 / 3 ALA A  59
ARG A  62
LYS A  66
 None
 0.57A 3kp3B-2ljpA:
undetectable		 3kp3B-2ljpA:
20.92