SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ljr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ALA A 158
VAL A 162
TRP A  84
 None
 0.76A 1av2C-2ljrA:
undetectable
1av2D-2ljrA:
undetectable		 1av2C-2ljrA:
5.67
1av2D-2ljrA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ARG A 107
ILE A 112
TRP A 115
 None
 1.14A 1nodB-2ljrA:
undetectable		 1nodB-2ljrA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ARG A 107
ILE A 112
TRP A 115
 None
 1.13A 1qomA-2ljrA:
undetectable		 1qomA-2ljrA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A  84
ALA A 158
VAL A 162
 None
 0.80A 2izqA-2ljrA:
undetectable
2izqB-2ljrA:
undetectable		 2izqA-2ljrA:
5.67
2izqB-2ljrA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 5 TRP A 193
ALA A 165
LEU A 151
ALA A 169
 None
 0.97A 2jstA-2ljrA:
undetectable
2jstB-2ljrA:
undetectable		 2jstA-2ljrA:
14.67
2jstB-2ljrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ARG A 107
ILE A 112
TRP A 115
 None
 1.14A 2nodB-2ljrA:
undetectable		 2nodB-2ljrA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		5 / 8 PHE A 200
GLY A 202
GLU A 204
ILE A  19
PHE A  20
 None
 1.00A 3aodA-2ljrA:
undetectable		 3aodA-2ljrA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ARG A 107
ILE A 112
TRP A 115
 None
 1.03A 3e7iB-2ljrA:
undetectable		 3e7iB-2ljrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		5 / 12 LEU A 114
GLY A 111
GLN A  12
ARG A  15
VAL A 127
 None
 1.38A 3gn8A-2ljrA:
undetectable		 3gn8A-2ljrA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 4 LEU A  54
PRO A  55
LEU A   7
ARG A  31
 None
 1.20A 3hcoB-2ljrA:
undetectable		 3hcoB-2ljrA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 7 ARG A 239
PRO A  13
SER A  67
GLY A 108
 None
 1.05A 3hcrB-2ljrA:
undetectable		 3hcrB-2ljrA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ALA A 158
VAL A 162
TRP A  84
 None
 0.76A 3l8lA-2ljrA:
undetectable
3l8lB-2ljrA:
undetectable		 3l8lA-2ljrA:
5.67
3l8lB-2ljrA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_B_ASDB126_1
(STEROID
DELTA-ISOMERASE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		5 / 10 SER A  11
LEU A  35
PHE A  45
VAL A  33
ASN A  49
 None
 1.39A 3nuvB-2ljrA:
0.0		 3nuvB-2ljrA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 ARG A 107
ILE A 112
TRP A 115
 None
 1.14A 3nw2B-2ljrA:
undetectable		 3nw2B-2ljrA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 8 LYS A  22
GLY A 202
LEU A 201
LEU A 167
 None
 0.84A 4po0A-2ljrA:
undetectable		 4po0A-2ljrA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 2ljr GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 193
ARG A 194
LEU A 143
 None
 0.81A 5dbyA-2ljrA:
undetectable		 5dbyA-2ljrA:
20.03