SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 8 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.91A 2eilP-2lklA:
undetectable
2eilW-2lklA:
undetectable		 2eilP-2lklA:
13.41
2eilW-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.91A 2eimP-2lklA:
undetectable
2eimW-2lklA:
undetectable		 2eimP-2lklA:
13.41
2eimW-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 6 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 1.01A 3wg7P-2lklA:
undetectable
3wg7W-2lklA:
undetectable		 3wg7P-2lklA:
13.41
3wg7W-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 5 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.90A 5x19C-2lklA:
undetectable
5x19J-2lklA:
undetectable		 5x19C-2lklA:
13.41
5x19J-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.86A 5z84C-2lklA:
undetectable
5z84J-2lklA:
undetectable		 5z84C-2lklA:
13.41
5z84J-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.84A 5z85C-2lklA:
undetectable
5z85J-2lklA:
undetectable		 5z85C-2lklA:
13.41
5z85J-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.87A 5zcoC-2lklA:
undetectable
5zcoJ-2lklA:
undetectable		 5zcoC-2lklA:
13.41
5zcoJ-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.87A 5zcqC-2lklA:
undetectable
5zcqJ-2lklA:
undetectable		 5zcqC-2lklA:
13.41
5zcqJ-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 LEU A  54
PHE A  21
LEU A  17
PHE A   9
 None
 0.81A 5zcqP-2lklA:
undetectable
5zcqW-2lklA:
undetectable		 5zcqP-2lklA:
13.41
5zcqW-2lklA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 2lkl ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		3 / 3 ASP A  48
LEU A  49
ARG A  56
 None
 0.86A 7dfrA-2lklA:
undetectable		 7dfrA-2lklA:
20.69