SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2lli PROTEIN AIR2
(Saccharomyces
cerevisiae) 		5 / 8 GLY A  29
ALA A  30
ASP A  33
ASP A  32
PRO A  21
 None
 1.38A 4eyrB-2lliA:
undetectable		 4eyrB-2lliA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 2lli PROTEIN AIR2
(Saccharomyces
cerevisiae) 		6 / 11 ARG A  13
GLY A  29
ALA A  30
ASP A  33
ASP A  32
PRO A  21
 None
 1.49A 4l1aA-2lliA:
undetectable		 4l1aA-2lliA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 2lli PROTEIN AIR2
(Saccharomyces
cerevisiae) 		4 / 5 THR A  31
HIS A  34
ALA A  30
ASP A  19
 None
ZN  A 204 (-3.7A)
None
None
 1.36A 5mfxA-2lliA:
undetectable		 5mfxA-2lliA:
10.42