SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2lll LAMIN-B2
(Homo
sapiens) 		3 / 3 GLN A 467
THR A 542
TRP A 534
 None
 1.16A 2rctA-2lllA:
undetectable		 2rctA-2lllA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 2lll LAMIN-B2
(Homo
sapiens) 		4 / 7 SER A 453
TYR A 501
ASN A 470
LEU A 503
 None
 1.44A 3lslA-2lllA:
undetectable
3lslD-2lllA:
undetectable		 3lslA-2lllA:
22.08
3lslD-2lllA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 2lll LAMIN-B2
(Homo
sapiens) 		4 / 7 ILE A 459
ARG A 485
VAL A 466
ILE A 483
 None
 0.97A 4zzbC-2lllA:
undetectable
4zzbD-2lllA:
undetectable		 4zzbC-2lllA:
16.72
4zzbD-2lllA:
16.72